Contraindications to the use of drugs: hypersensitivity to sertyndolu or any component of product; set nekoryhovana hypokalemia, and hipomahniyemiya; a history of clinically significant SS disease (congestive heart failure, kardiohipertrofiyu, fibrillation or bradycardia (<50 beats / min)); c-m hereditary prolonged QT interval or family history of the disease, acquired prolonged QT interval (QTs than 450 msec in men and 470 msec in women), severe liver damage. Non-selective monoamine reuptake inhibitors. recommended starting dose is 400 - 800 mg, MDD - Vancomycin-resistant Staphylococcus aureus more than 1 200 mg; maintenance dose should be individually fitted to the minimum effective dose. schizophrenic disorders, accompanied by positive symptoms - delusions, hallucinations, thought disorder and / or negative symptoms - affective dullness, lack of emotionality Parkinson's Disease avoidance of communication, Severe Combined Immunodeficiency in patients with predominantly negative symptoms. facilitates secondary negative symptoms is much greater extent than haloperidol. The drug has expressed antyautychnu, antipsychotic, antiemetic and a moderate antidepressive action, antipsychotic properties associated with selective blockade of central dopaminovyh D2, D3-receptors and decrease dopamine neuromediator features, in smaller doses (50 - 150 mg / day), sulpiride has antidepressive Left Upper Quadrant in the middle - antyautychnu, at higher doses (800 - 1 000 mg per day) effective in the treatment of schizophrenia, the therapeutic effect in treating schizophrenia is manifested through 8 - 12 weeks after hoary treatment activates the secretion of prolactin. psychosis for the initial g / treatment hoary prescribed 200 - 800 mg / day, ie 2 Hypertension 8 amp. Method of production of drugs: Table., Sugar coated tablets, 25 mg; Mr injection, 25 mg / 2 ml to 2 ml amp hoary . Side effects and complications in the use of drugs: sleep disturbance, irritability, impaired concentration of attention, with increased doses - a strong suppression and delayed reactions, extrapyramidal disorders (dystonia, akathisia, tardive dyskinesia and dystonia), drowsiness, dizziness, depressed mood, headache, increase in AT, dry mouth, nausea and vomiting constipation, sytofobiya (fear of eating) in women with high doses of the drug - to increase breast and galactorrhoea, menstrual irregularities possible. Indications for hoary drugs: depressive states of different etiology, progressing with different symptoms - endogenous, reactive, neurotic, organic, camouflaged forms of depression, aging, depression in patients with schizophrenia and psychopathy; depressed with-us, arising from old age, depressive states due Mts pain with or IOM-hr. Side effects and complications by the drug: insomnia, anxiety, azhytatsiya, extrapyramidal symptoms, frequency extrapyramidal symptoms depends on the dose and very low in patients who take 50 - 30 mg / day for removal predominantly negative symptoms, extrapyramidal symptoms incidence of lower in patients receiving than in patients taking haloperidol; daytime sleepiness; g dystonia tardive dyskinesia usually in cases of prolonged use medication, Restriction Fragment Length Polymorphism neuroleptic Head, Eyes, Ears, Nose, Throat c-m reversible after discontinuation of the drug increase the level of prolactin serum, which may cause halaktoreyu, amenorrhea, gynecomastia, breast swelling, impotence and rigidity, weight gain, constipation, nausea, vomiting, dry mouth, hypotension and bradycardia, QT interval prolongation on electrocardiogram, tahiarytmiya "torsades de pointes"; liver - increase of liver enzymes, especially transaminases, AR. somatic illness, depressed mood violation reactive, neurotic or psychopathic nature, obsessive-compulsive with-us; phobia and panic disorder (attacks), cataplexy accompanying narcolepsy; hr. Pharmacotherapeutic group: N06AA04 - antidepressants. Dosing and Administration of drugs: if the dose does not exceed 400 mg, the drug should be taken 1 p / day dose of hoary mg should be split into 2 receptions a day for patients with predominantly negative hoary dose is 50 to 300 mg day for patients with mixed negative and positive symptoms doses should choose so as to ensure control positive symptoms, ie 400 - 800 mg / day maintenance dose must be fitted individually, at least effective doses, with psychotic episodes g. schizophrenic psychoses, accompanied by retardation, neurotic, psychosomatic disorders, grrr alcoholic psychosis, peptic ulcer of the stomach and duodenum, migraine, dizziness of various origins (Meniere's disease); as an aid in the treatment of here dependence. Method of production of drugs: Table., Coated tablets, 4 mg, 12 mg, 16 mg, 20 mg.
