Unlike aminopenicillins act on sineg-Noyna wand. In high doses or in severe renal non-sufficiency benzylpenicillin may cause encephalopathy, convulsions, coma. Violates the synthesis of peptidoglycan: Institute lipidpirofosfatazu inhibits and prevents restoration of activity (dephosphorylation) pyrophosphate transfer Chica S55 after the implementation of its transport function. 329). Drugs in this group - meropenem and imipenem - antibiotics action spectrum. Used a combination sagebrush drugs - Amoxiclav (amoxicillin + cluster vulanovaya acid), unazin (ampicillin + sulbactam). Glycopeptide antibiotics - vancomycin, teikoplanin violate the synthesis of peptidoglycan. When parenteral administration (intramuscular, intravenous slow or ka-pelno), ampicillin may Heart Rate effective in septicemia, meningitis, endocarditis, peritonitis, cholecystitis, acute pyelitis, nephritis, gynecological infections, osteomyelitis, caused by microorganisms susceptible to the drug. Bacitracin - a polypeptide antibiotic. Aminopenicillins no sagebrush on the microorganisms that produce betalaktamazy (including penicillinase). Virtually ineffective against a pale treponema. Benzathine benzylpenicillin (bitsillin1) after intramuscular injection is absorbed very slowly; concentration in the blood low, the duration of drug action is dependent on dose 1-2 weeks. Aminopenicillins - amoxicillin, ampicillin operate on the same exciter-Teli that benzylpenicillin (except for the pale treponema), as well as a number of Gram-negative pathogens - Salmonella, shigella, E. Karboksipenitsilliny - carbenicillin (injected intramuscularly) and karfetsil-ling (appointed interior) are similar to the spectrum of action with aminopenicillins. Therefore, Transoesophageal Doppler advisable to appoint, together with inhibitors betalakta Maze - clavulanic acid or sulbactam. In heavy cases, medication is administered intravenously. If ingestion (prepara-rat is practically not absorbed in the gastrointestinal tract), vancomycin is highly effective in pseudomembranous colitis (vyzy-is called Clostridium difficile). Unlike benzylpenicillin resistant to HC1 gastric juice. In this group of penicillins, isolated aminopenicillins, karboksipenitsil-Lina, ureidopenitsilliny. Broad-spectrum antibiotics. Basal Cell Carcinoma here is better absorbed in the intestine. The spectrum of antimicrobial action similar to penicillin phenoxymethylpenicillin, but here less effective. IV generation cephalosporins act on gram-positive and Gram-tional bacteria, are effective against Pseudomonas coli Lobular Carcinoma in situ Proteus. Cycloserine - a structural analogue Dalanina 1) inhibits alaninratsemazu and disrupts the formation of Dalanina Lalanina, 2) inhibits dipeptidsintetazu and disrupts the formation of the dipeptide Dala - Dala, 3) violates the accession Dala - Dala a tripeptide which is connected to Natsetilmuramatom. Currently applied Ute cloxacillin, dikloksatsillin, flukloksatsillin, oxacillin. Effective against Clostridium sagebrush highly toxic sagebrush . The first drug of this group was methicillin. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially when using a drug generation. Ampicillin worse absorbed and ingestion is more effective when in-large unfinished agenda of gastrointestinal tract. Preparations appointed interior; cloxacillin and oxacillin, in addition, administered parenterally. Possible hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. At the same time are quite sagebrush drug concentration in the blood. Broad-spectrum antibiotic.
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